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药物肽

Drug peptide

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Bivalirudin

发布时间:2022-06-08作者:南京大奖888国际生物科技有限公司

CAS No.:
128270-60-0

Molecular formula:
C98H138N24O33

Molecular Weight:
2180.29

Amino acids sequence:
H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH

Application:
Bivalirudin is a 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot bound, at the catalytic site and the anion-binding exosite, thereby preventing the formation and activation of fibrin, factor XIIIa, and other coagulation factors. This drug is primarily used during coronary angioplasty procedures, in combination with aspirin, in patients with unstable angina.

Notes: For research use only

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